Publications
Barth Syndrome
Barth syndrome cardiomyopathy: targeting the mitochondria with elamipretide...
ReadA phase 2/3 randomized clinical trial followed by an open-label extension to evaluate the effectiven...
ReadTAZPOWER Analysis: Elamipretide Significantly Improves Disease Symptomatology versus Natural History...
ReadChanges in Plasma and Urinary Metabolites After Elamipretide in Barth Syndrome Patients: Analyses fr...
ReadEfficacy and Tolerability of Elamipretide in Patients with Barth Syndrome: Results from TAZPOWER, a ...
ReadTAZPOWER: Biomarker Cardiolipin Ratios and Clinical Symptom Severity from a Randomized, Double-Blind...
ReadTAZPOWER: Study Design of a Randomized, Double-Blind, Placebo-Controlled Crossover and Extension Tri...
ReadTAZPOWER: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover and Open-Label Exten...
ReadStudy Design of TAZPOWER: A Randomized, Double-Blind, Placebo-Controlled Crossover and Extension Tri...
ReadNew Targets for Monitoring and Therapy in Barth Syndrome...
ReadBloodspot Assay Using HPLC–Tandem Mass Spectrometry for Detection of Barth Syndrome...
ReadBarth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxyg...
ReadBarth Syndrome: Cellular Compensation of Mitochondrial Dysfunction and Apoptosis Inhibition Due to C...
ReadLoss of Protein Association Causes Cardiolipin Degradation in Barth Syndrome (Author Manuscript)...
ReadMTP131, a cardiolipin targeting peptide, improves mitochondrial activity in the failing human heart...
ReadPhase 2a Clinical Trial of Mitochondrial Protection (Elamipretide) During Stent Revascularization in...
ReadElamipretide Treatment in an Infant with Sengers Syndrome...
ReadElamipretide in Patients with Barth Syndrome: A Randomized, Double Blind, Placebo-Controlled Clinica...
ReadMechanism of Action
Cardiolipin and Mitochondrial Cristae Organization...
ReadRole of Cardiolipin in Mitochondrial Signaling Pathways...
ReadRole of Cardiolipin Alterations in Mitochondrial Dysfunction and Disease...
ReadSerendipity and the Discovery of Novel Compounds That Restore Mitochondrial Plasticity...
ReadGuiding Ageing Research Into Maturity...
ReadMitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle perform...
ReadElamipretide Improves Skeletal Muscle Function in Elderly Subjects: Results from a Randomized, Doubl...
ReadNeurology
The Cardiolipin-Targeting Compound SBT-272 Attenuates Neurodegeneration, Delays the Onset of Neurolo...
ReadOphthalmic/Dry Age-Related Macular Degeneration/Leber Hereditary Optic Neuropathy
Elamipretide Topical Ophthalmic Solution for the Treatment of LHON: Outcomes and Efficacy...
ReadElamipretide, a mitochondrial-targeted drug, for the treatment of vision loss in dry AMD with high r...
ReadEffects of the Mitochondria-Targeted Drug Elamipretide on Leakage-Independent Vision Loss in Fellow ...
ReadA mitochondrial therapeutic reverses visual decline in mouse models of diabetes...
ReadRole of Mitochondrial Dysfunction in Dry Age-Related Macular Degeneration...
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