Committed to Innovation in Mitochondrial Therapies

Passionate for Patients

At Stealth BioTherapeutics, our work is personal. We believe strongly in the potential of our science to deliver new treatment solutions and improve quality of life for patients with diseases involving mitochondrial dysfunction, including the more than 250 different genetic mutations that can cause mitochondrial disease for which there are currently no FDA-approved treatments.

Disease and Disorders Associated with Mitochondrial Dysfunction

Stealth BioTherapeutics is an innovative biopharmaceutical company developing therapies to treat mitochondrial dysfunction associated with genetic mitochondrial diseases and common diseases of aging. Our team works with patients and advocacy organizations to better understand their journey and raise awareness of the unmet need our programs seek to address.

Mitochondrial Myopathy

Primary (inherited) mitochondrial myopathy, or PMM, is characterized by debilitating skeletal muscle weakness and exercise intolerance. We estimate that approximately 70,000 individuals in the United States are diagnosed with this syndrome. There are no therapies approved by the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA) for the treatment of primary mitochondrial myopathy.

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Ocular Disease

Leber’s hereditary optic neuropathy, or LHON, is characterized by central vision loss. We estimate that approximately 10,000 individuals in the United States are diagnosed with LHON. There are no therapies approved by the FDA for the treatment of LHON.

Dry age-related macular degeneration, or dry AMD, the leading cause of blindness among older adults in the developed world, is characterized by symptoms such as distorted vision, reduction in low luminance visual acuity, reduced overall visual acuity and blurred vision. We estimate that dry AMD impacts more than 1.7 million individuals in the United States.  There are no FDA or EMA approved treatments for the treatment of dry AMD.

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Leadership

We are invested in patient-focused therapeutic development and driven by a desire to help patients with unmet clinical needs.

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Grants & Sponsorships

We support programs and initiatives that offer health care providers and patient communities access to educational information.

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Careers

We are a high-energy, innovative company with a hard-working team striving to further our mission of patient-focused therapeutics development.

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